Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 439-750-2 | CAS number: 183487-56-1
Background opacity: for all examined corneas (n=27), background opacity ranged between 0 and 3, indicating that no corneas had to be excluded from the experimental test design and replaced by another one.
In the first test, first repeat and second repeat, each negative control cornea showed an opacity, a permeability and an in vitro score which fell within the laboratory range of historical data. In all studies, the corneas treated with the positive control showed a marked increase in opacity and permeability. Imidazole (20g/g%) was detected as a very severe eye irritant according to the historical data. Based on the findings in the negative and positive control group, it was concluded that the test conditions were optimal for the evaluation of the potential of T002113 to induce opacity and permeability.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again