Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
October 13, 1997 - February 5, 1998
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1998
Report date:
1998

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
Deviations:
no
Principles of method if other than guideline:
.
GLP compliance:
yes
Test type:
acute toxic class method
Limit test:
yes

Test material

Constituent 1
Reference substance name:
SP6012
IUPAC Name:
SP6012
Details on test material:
See study report attached

Test animals

Species:
rat
Strain:
Crj: CD(SD)
Sex:
male/female
Details on test animals or test system and environmental conditions:
See study report attached

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
unchanged (no vehicle)
Details on oral exposure:
See study report attached
Doses:
5000 mg/kg bw
No. of animals per sex per dose:
5 Males/5 Females per dose
Control animals:
no
Details on study design:
See study report attached
Statistics:
None required for study

Results and discussion

Preliminary study:
Estimated oral LD50 value for male and female rats determined to be > 5,000 mg/kg
Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Mortality:
No deaths occurred during the study
Clinical signs:
other: See study report attached
Gross pathology:
No test material related lesions found at necropsy
Other findings:
See study report attached

Any other information on results incl. tables

See study report attached

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Remarks:
Migrated information
Conclusions:
Oral LD50 value for male and female rats determined to be > 5,000 mg/kg
Executive summary:

See study report attached