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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
19/05/2017 to 28/07/2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
not specified
GLP compliance:
no
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Type of method:
other: not reported
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 160504
- Expiration date of the lot/batch: data not available
- Purity test date: 29/05/2017 (manufacturing date)
Key result
Water solubility:
793 g/L
Conc. based on:
test mat.
Incubation duration:
>= 24 - <= 72 h
Temp.:
24.5 °C
pH:
>= 7 - <= 8
Details on results:
Solubility at 24h: 767.9 g/L
Solubility at 48h: 812.7 g/L
Solubility at 72h: 799.4 g/L
Solubility (mean): 793 g/L ± 70 g/L at 24-25ºC and pH 7-8.
Conclusions:
Trimethylamine N-oxide has a water solubility of 793 g/L ± 70 g/L at 24-25ºC and pH 7-8.
Executive summary:

Trimethylamine N-oxide has a water solubility of 793 g/L ± 70 g/L at 24-25ºC and pH 7 -8.

Description of key information

Method equivalent to OECD Guideline 105. Not GLP but ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories). Water solibility was determined at 24-25ºC and pH 7-8.

Solubility at 24h: 767.9 g/L

Solubility at 48h: 812.7 g/L

Solubility at 72h: 799.4 g/L

Solubility (mean): 793 g/L ± 70 g/L

Key value for chemical safety assessment

Water solubility:
793 g/L
at the temperature of:
24.5 °C

Additional information