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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

A nitrification inhibition test with Zn sulfate on activated slugde originating from a municipal wastewater treatment plant was performed leading to a NOEC of 100 µg Zn/L.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
100 µg/L

Additional information

Several data were available for this endpoint. Formerly (ECB 2008), and in the REACH-registrations of a number of zinc substances of November 2010, a PNEC of 52 µg/L for STP was derived, based on the lowest EC50 of 5.2 mg Zn/L observed in a sludge respiration inhibition test (Dutka et al. 1983). According to the guidance (ECHA preference should be given to nitrification inhibition because respiration inhibition is a less sensitive endpoint. A study conducted by Juliastuti et al. (2003) reported a NOEC of 0.1 mg Zn/L in an ISO 9509 nitrification inhibition test. Applying the rules for PNEC setting (ECHA R.10, table R.10.6) this result yields a PNEC STP of 100 µg Zn/L (AF of 1).