Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
skin irritation: in vitro / ex vivo
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
publication
Title:
Hygiene of labour
Author:
Zaugliikov S. D., Predtechenskiy M. B
Year:
1967
Bibliographic source:
Not specified

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
No information about the principles of method available.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Isopropyl nitrate
EC Number:
216-983-6
EC Name:
Isopropyl nitrate
Cas Number:
1712-64-7
Molecular formula:
C3H7NO3
IUPAC Name:
propan-2-yl nitrate
Test material form:
liquid

In vitro test system

Test system:
other: not specified
Source species:
rat
Source strain:
not specified
Vehicle:
not specified

Test animals

Species:
rat
Strain:
not specified

Test system

Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Amount / concentration applied:
Not specified.
Duration of treatment / exposure:
Not specified.

Results and discussion

In vitro

Results
Irritation / corrosion parameter:
other: no data about the parameter
Positive controls validity:
valid
Remarks on result:
positive indication of irritation

Applicant's summary and conclusion

Interpretation of results:
Category 2 (irritant) based on GHS criteria