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Toxicological information

Skin sensitisation

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Administrative data

Endpoint:
skin sensitisation: in vivo (non-LLNA)
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Justification for type of information:
No result was calculated by the (Q)SAR

Data source

Reference
Reference Type:
other: (Q)SAR Toolbox prediction Category report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
QSAR read-across analysis.
GLP compliance:
no
Justification for non-LLNA method:
No indormation available about testing using LLNA-method.

Test material

Constituent 1
Chemical structure
Reference substance name:
Isopropyl nitrate
EC Number:
216-983-6
EC Name:
Isopropyl nitrate
Cas Number:
1712-64-7
Molecular formula:
C3H7NO3
IUPAC Name:
propan-2-yl nitrate
Test material form:
liquid

In vivo test system

Study design: in vivo (non-LLNA)

Induction
Route:
other: not specified
Vehicle:
not specified
Adequacy of induction:
not specified

Results and discussion

Positive control results:
Positive result for skin sensitisation.

In vivo (non-LLNA)

Results
Reading:
1st reading
Clinical observations:
positive result
Remarks on result:
positive indication of skin sensitisation

Applicant's summary and conclusion

Interpretation of results:
other: positive result for skin sensitisation.

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