Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
28 July 2017 to 31 August 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
capillary method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid
Details on test material:
MIT.HCl as manufacured has a purity of >99.9% therefore the technical grade and analytical grade are identical
Specific details on test material used for the study:
Batch Number 10013913, Purity >99.9%, Expiry Date 30 November 2018
Analytical grade and technical grade material are identical

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
>= 165 - <= 170 °C
Atm. press.:
ca. 99.04 kPa
Decomposition:
no
Sublimation:
no

Any other information on results incl. tables

 Experiment number  Stage A (°C)  Stage B (°C)  Stage C (°C) Stage D (°C)   Stage E (°C)
 1 165.0 166.0 167.5 170.0  170.3 
 2 165.0 165.0 167.8 169.5 169.7 
 3 165.0 166.0  167.5 169.5  170.1
 Mean  165.0  165.7  167.6  169.7 170.0 

Stage A: Begining of melting/wet point

Stage B: Shrinkage point

Stage C: Collapse point

Stage D: Uquefying point

Stage E: Final stage of melting

Applicant's summary and conclusion

Conclusions:
In conclusion, the test item 2-Methyl-4-Isothiazolin-3-One Hydro-chloride melted in the range of 165.0 °C to 170.0°C (438.2 K to 443.2 K).
Executive summary:

The test item 2-Methyl-4-Isothiazolin-3-One Hydrochloride melted in the range of 165.0 °C to 170.0°C (438.2 K to 443.2 K).