Registration Dossier

Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
28 July 2017 to 31 August 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 103 (Boiling Point)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
Deviations:
no
Principles of method if other than guideline:
For the determination of the boiling point, the capillary method according to Siwoloboff was used. A small amount of the test item was heated in the electronic controlled sample block and the temperature of around the sample was displayed. The sample was observed visually while raising the temperature. A phase transformation from liquid to vapour usually is deduced by the formation of steam bubbles leaving the inserted boiling capillary.
The test item was assessed visually for any possible changes in its appearance, consistency and colour. The initial temperature of boiling or other effects observed were registered with the correspond-ing heating temperature
GLP compliance:
yes (incl. certificate)
Type of method:
other: Capillary method using electronic controlled heating system

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid
Details on test material:
MIT.HCl as manufacured has a purity of >99.9% therefore the technical grade and analytical grade are identical
Specific details on test material used for the study:
Batch Number 10013913, Purity >99.9%, Expiry Date 30 November 2018
Analytical grade and technical grade material are identical

Results and discussion

Boiling point
Key result
Atm. press.:
ca. 99.04 kPa
Decomposition:
yes
Decomp. temp.:
ca. 190 °C

Applicant's summary and conclusion

Conclusions:
In conclusion, for 2-Methyl-4-Isothiazolin-3-One Hydrochloride no boiling point according to the criteria described in the guideline could be observed up to 400 °C. The atmospheric pressure was 99.04 kPa.
Executive summary:

For 2-Methyl-4-Isothiazolin-3-One Hydrochloride no boiling point according to the criteria described in the guideline could be observed up to 400 °C.The atmospheric pressure was 99.04 kPa.