Registration Dossier

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Estimated logKow > 10

Key value for chemical safety assessment

Log Kow (Log Pow):
10

Additional information

The predicted value of logKow is out of the recommended range by Shake Flask Method (OECD TG 107 applicable in range between -2 and 4) and by HPLC Method (OECD TG 117 applicable in range between 0 and 6). The multi-constituent substance " Reaction mass of dodecane-1-thiol and tridodecyl trithiophosphite is very difficult to detect by HPLC because it has no chromophore and it is low water soluble so the experimental test for logKow is difficult to perform and in any case the experimental value is expected highly positive.

Estimated logKow > 10 was carried out by algorithm GALAS as implemented in ACD/Percepta software using as input the data related to its most abundant component, i.e. tridodecyl trithiophosphite.

For this reason the calculated value of logKow has been reported as key value for the Chemical Safety Assessment.