Registration Dossier
Registration Dossier
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Reaction mass of 3,3'-(1E,1'E)-(4,4'-(6-(bis(2-hydroxyethyl)amino)-1,3,5-triazine-2,4-diyl)bis(azanediyl)bis(3-methoxy-4,1-phenylene))bis(diazene-2,1-diyl)dibenzenesulfonic acid and disodium 3,3'-[[6-[bis(2-hydroxyethyl)amino]-1,3,5-triazine-2,4-diyl]bis[imino(3-methoxy-4,1-phenylene)azo]]bis[benzenesulphonate]
EC number: 943-704-1 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Oral LD50 (female) > 2000 mg/kg bw
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
No data on target substance was available, thus a read across approach with Similar Substance 01 was followed. Further details are available in section 13.
Acute oral toxicity of Similar Substance 01 was assessed upon single oral administration to Sprague-Dawley CD strain rats, according to OECD guidelines 423 and EU method B1 tris. A group of three fasted females was treated with the test material at a dose level of 2000 mg/kg bodyweight. This was followed by a further group of three fasted females at the same dose level. There were no deaths during the experiment; no signs of systemic toxicity was recorded. All animals showed expected gains in bodyweight over the study period.
No abnormalities were noted at necropsy.
Justification for classification or non-classification
According to the CLP Regulation (EC) No 1272/2008, 3.1 Acute toxicity section, substances can be allocated to one of four toxicity categories based on acute toxicity by the oral, dermal or inhalation route according to the numeric criteria. Acute toxicity values are expressed as (approximate) LD50 (oral, dermal) or LC50 (inhalation) values or as acute toxicity estimates (ATE).
Based on an oral LD50 value greater than 2000 mg/kg body weight, no classification for acute oral toxicity applied to target substance.
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