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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
24-Nov-2014 to 03-Dec-2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reference:
Composition 0
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. certificate)
Remarks:
Staatliches Gewerbeaufsichtsamt Hildeshelm
Type of method:
flask method
Test material information:
Composition 1
Key result
Water solubility:
0.231 g/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
6.3

Results

Preliminary Test (non GLP)

In the preliminary test a water solubility of approx. 120 mg/L was achieved. 

 

Main test

Water solubility results at 20 °C

Pre-incubation time

Replicate No.

Concentration1)

(g/L)

Mean

24 h

1

0.254

0.238

2

0.222

48 h

1

0.213

0.223

2

0.233

72 h

1

0.264

0.232

2

0.200

Mean (24 – 72 h)

 

 

0.231

Deviation (%)

 

 

6.84

 

1) Mean value of two injections, weighing factor and dilution factor of 62.5 were taken into account

 

Conclusions

The solubility of the test item was determined to be 0.231 g/L (pH 6.3) at 20 ± 0.5 °C.

Conclusions:
A water solubility value of 2.31E-01 g/L (at 20 °C, pH 6.3) was determined for the test substance according to OECD 105 (1995).

Description of key information

Water solubility: 2.31E-01 g/L at 20 °C, pH = 6.3 (OECD 105, flask method)

Key value for chemical safety assessment

Water solubility:
0.231 g/L
at the temperature of:
20 °C

Additional information