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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Endpoint summary

Administrative data

Description of key information

Appearance:

Chemical 4-(2-aminoethyl) phenol physically appear as a crystalline solid.

Melting point:

Melting point of chemcial 4-(2-aminoethyl) phenol is determine in the range between 164-165 Deg C.

Boiling Point:

Boiling point of chemcial 4-(2-aminoethyl) phenol is determine in the range between 205-207 Deg C at pressure 25 mmHg.

Density:

Density of chemical 4-(2-aminoethyl) phenol is determine to be 1.0630 g/cm3 at temperature 20 Deg C.

Particle size distribution:

The particle size distribution of 4-(2-aminoethyl)phenol was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 150 micron to 53 micron.

Vapour pressure:

The estimated vapour pressure of 4-(2-aminoethyl) phenol at temperature 25 deg C was 0.4226 Pa

Partition coefficient:

Based on the available data from authoritative and modelling databases, the partition coefficient (log Pow) value of the substance 4 -(2 -Aminoethyl)phenol was estimated to be 0.86. Based on this value, chemical 4 -(2 -Aminoethyl)phenol can be considered to be hydrophilic in nature.

Water solubility:

Water solubility of chemical 4-(2-aminoethyl) phenol is determine to be 10400 mg/L at temperature 15 Deg C. From this solubility value it is concluded that chemical 4-(2-aminoethyl) phenol is very soluble in water.

Surface tension:

In accordance with column 2 of Annex VII of the REACH regulation, the study need only be conducted if surface activity is a desired property of the chemical. 4-(2-Aminoethyl)phenol (CAS no. 51-67-2) is used as a flavoring agents. For this use, surface activity is not an important property. Hence this study was considered for waiver.

Flash point:

The study does not need to be conducted because the flash point is only relevant to liquids and low melting point solids.

Auto flammability:

4-(2-aminoethyl)phenol did not catch fire on being exposed to air at room temperature of 27°Cpressure of 966 hPa. This indicates that 4-(2-aminoethyl)phenol is not auto-flammable.

Flammability:

4-(2-aminoethyl)phenol does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 4-(2-aminoethyl)phenol is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 4-(2-aminoethyl)phenol was considered non-flammable.

Explosiveness:

The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.

Oxidizing properties:

The study does not need to be conducted because the substance is a solid.

Additional information

Appearance:

Chemical 4-(2-aminoethyl) phenol physically appear as a crystalline solid.

From other reliable sources & authoritative databases it is concluded that chemical 4 -(2 -aminoethyl) phenol appear as a solid having pellets or needles.

Melting point:

Melting point of chemcial 4-(2-aminoethyl) phenol is determine in the range between 164-165 Deg C.

From other reliable sources & authoritative datbases it is concluded that melting point of chemcial 4 -(2 -aminoethyl) phenol is in the range between 161-165 Deg C.

Boiling Point:

Boiling point of chemcial 4-(2-aminoethyl) phenol is determine in the range between 205-207 Deg C at pressure 25 mmHg.

From other reliable sources & authorative databases it is concluded that boiling point of chemcial 4 -(2 -aminoethyl) phenol is to be 206 Deg C at pressure 25 mmHg & 175 -181 Deg C at pessure 8 mmHg & 166 Deg C at pressure 2 mmHg.

Density:

Density of chemical 4-(2-aminoethyl) phenol is determine to be 1.0630 g/cm3 at temperature 20 Deg C.

From other reliable sources & authoritative databases it is concluded that density of chemical 4 -(2 -aminoethyl) phenol is 1.0545 g/cm3 at temperature 23.33 Deg C.

Particle size distribution:

The particle size distribution of 4-(2-aminoethyl)phenol was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 150 micron to 53 micron.

Vapour pressure:

The estimated vapour pressure of 4-(2-aminoethyl) phenol at temperature 25 deg C was 0.4226 Pa

Partition coefficient:

Based on the available data in a key study from authoritative and modelling databases, the partition coefficient (log Pow) value of the substance 4 -(2 -Aminoethyl)phenol was estimated to be 0.86.

In a supportingstudy from peer reviewed journal,the partition coefficient (log Pow) value of the substance 4 -(2 -Aminoethyl)phenol was estimated to be in the range from 0.97 – 1.13, respectively.

Additional study from authoritative and modelling database indicates that the octanol waterpartition coefficient (log Pow) value of the substance 4 -(2 -Aminoethyl)phenol was estimated to be 0.72.

Another supporting study from modelling database indicates that the partition coefficient (log Pow) value of the substance 4 -(2 -aminoethyl) phenol was estimated to be 0.782 ± 0.205 at 25°C.

Thus, based on the available information, the logPow valueof the test substance 4 -(2 -Aminoethyl)phenol ranges from 0.72 to 1.13, respectively. On the basis of this estimated value, chemical 4 -(2 -Aminoethyl)phenol can be considered to be hydrophilic in nature.

Water solubility:

Water solubility of chemical 4-(2-aminoethyl) phenol is determine to be 10400 mg/L at temperature 15 Deg C. From this solubility value it is concluded that chemical 4-(2-aminoethyl) phenol is very soluble in water.

From other reliable sources & authoritative databases it is concluded that water solubility of chemical 4 -(2 -aminoethyl) phenol is determine to be 10526 mg/L at temperature 15 Deg C, 11000 mg/L at temperature 15 Deg C & 10500 mg/L at temperature 20 Deg C. From this solubility values it is concluded that chemical 4-(2-aminoethyl) phenol is very soluble in water.

Surface tension:

In accordance with column 2 of Annex VII of the REACH regulation, the study need only be conducted if surface activity is a desired property of the chemical. 4-(2-Aminoethyl)phenol (CAS no. 51-67-2) is used as a flavoring agents. For this use, surface activity is not an important property. Hence this study was considered for waiver.

Flash point:

The study does not need to be conducted because the flash point is only relevant to liquids and low melting point solids.

Auto flammability:

4-(2-aminoethyl)phenol did not catch fire on being exposed to air at room temperature of 27°Cpressure of 966 hPa. This indicates that 4-(2-aminoethyl)phenol is not auto-flammable.

Flammability:

4-(2-aminoethyl)phenol does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 4-(2-aminoethyl)phenol is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 4-(2-aminoethyl)phenol was considered non-flammable.

Explosiveness:

The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.

Oxidizing properties:

The study does not need to be conducted because the substance is a solid.