Registration Dossier
Registration Dossier
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EC number: 250-426-8 | CAS number: 31001-77-1
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
log Kow [3-[dimethoxy(methyl)silyl]propanethiol]: 2.9 at 20°C (QSAR)
log Kow [3-(dihydroxymethylsilyl)propanethiol]: 0.5 at 20°C (QSAR)
log Kow [methanol]: -0.82 to -0.64
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 2.9
- at the temperature of:
- 20 °C
Additional information
The requirement to conduct a n-octanol/water partition coefficient for the substance is waived because in contact with water, the substance hydrolyses rapidly (half-life 1.4 h at pH 7, 0.1 h at pH 4, 0.03 h at pH 9 and 20-25°C to form 3-(dihydroxymethylsilyl)propanethiol and methanol.
The log Kow of the substance and its silanol hydrolysis product have been predicted using validated QSAR estimation methods to be 2.9 and 0.5 respectively.
Methanol has a reported log Kow of -0.82 to -0.64 (OECD 2004).
Reference:
OECD (2004): SIDS Initial Assessment Report for SIAM 19, Berlin, Germany, 18-20 October 2004, Methanol, CAS 67-56-1.
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