Registration Dossier
Registration Dossier
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EC number: 617-606-1 | CAS number: 84656-75-7
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- no data
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
- Deviations:
- yes
- Remarks:
- doses applied exceed the limit dose
- GLP compliance:
- not specified
- Test type:
- acute toxic class method
- Limit test:
- yes
Test material
- Reference substance name:
- (1r,1's,4r,4'r)-4-(4-methylphenyl)-4'-propyl-1,1'-bi(cyclohexane)
- EC Number:
- 617-606-1
- Cas Number:
- 84656-75-7
- Molecular formula:
- C22H34
- IUPAC Name:
- (1r,1's,4r,4'r)-4-(4-methylphenyl)-4'-propyl-1,1'-bi(cyclohexane)
- Test material form:
- solid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- Temperature:24-25°C
Humidity: 60-75 %
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- not specified
- Doses:
- 5860, 7620, and 9900 mg/kg bw
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 9 900 mg/kg bw
- Based on:
- test mat.
- Mortality:
- no mortality was observed
- Clinical signs:
- no clinical signs have been reported
- Body weight:
- no effects have been reported
- Gross pathology:
- no abnormalities have been reported
- Other findings:
- no other findings
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The LD50 oral (rat) exceeds 9900 mg/kg bw.
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