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Toxicological information

Carcinogenicity

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Description of key information

Key value for chemical safety assessment

Carcinogenicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

According to Regulation (EC) No. 1907/2006, Annex X, item 8.9.1, column 2, testing of carcinogenicity is not indicated, as several studies investigating the genetic toxicity of N-methyl-N-(C18-(unsaturated)alkanoyl)glycine in-vitro have shown that the substance is not genotoxic. Moreover, the subchronic repeated dose toxicity test via the oral route conducted with N-methyl-N-(C18-(unsaturated)alkanoyl)glycine revealed no substance-related adverse effects indicative for carcinogenicity such as hyperplasia or pre-neoplastic changes (e. g. metaplasia).

Justification for classification or non-classification