Registration Dossier
Registration Dossier
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EC number: 203-636-9 | CAS number: 108-99-6
Endpoint summary
Administrative data
Description of key information
Additional information
The bioconcentration factor (BCF) for 3-methylpyridine was determined by two methods: direct measurement and by estimation by QSAR. The two values are similar; the directly measured value validates the estimated QSAR value, and the use of the QSAR model for the estimation of BCF in this chemical category (pyridine, 2-methylpyridine, 3-methylpyridine and 4-methylpyridine).
An OECD guideline study conducted by the Japan National Institute of Technology and Evaluation (NITE) resulted in a BCF of 2.6 L/kg wet weight as measured in Cyprinus carpio (common carp), a freshwater fish. This value was used as the BCF for aquatic habitats.
The BCF was also estimated by BCFBAF v3.00, a model within Estimation Programs Interface Suite™ for Microsoft ® Windows, v4.00. The estimated BCFof 2.876 L/kg wet weight is useful to evaluate the potential for bioaccumulation in both aquatic and terrestrial habitats, and was used as the BCF for terrestrial habitats.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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