Registration Dossier
Registration Dossier
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EC number: 203-636-9 | CAS number: 108-99-6
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The EC50 for freshwater invertebrates represents the 48-hour EC50 reported by Weytjens and Wils (1991) on Daphnia magna, in accordance with OECD Guideline 202, compliant with GLP. This LC50 was the key value for short-term toxicity to aquatic invertebrates for all chemicals in the category (i.e., pyridine, 2-methylpyridine, 3-methylpyridine and 4-methylpyridine).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 320 mg/L
Additional information
The point of departure for the derivation of the PNECaquaticwas the EC50 value from the 72-hour Selenastrum capricornutum (aquatic alga) assay and the EC50 value from the 48-hour Daphnia magna (aquatic invertebrate) conducted by Weytjens and Wils (1991) on 3-methylpyridine; the These two EC50 values (which were equivalent) represented the lowest of the short-term toxicity values for each of three trophic levels (fish, aquatic invertebrates and aquatic algae), and were selected as the point of departure for the derivation of the PNECaquatic for the chemical category including pyridine, 2-methylpyridine, 3-methylpyridine and 4-methylpyridine.
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