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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

EC50 (72h) = 32.56 mg/L, NOEC (72h) = 11.25 mg/L (nominal, based on active matter) for Scenedesmus subspicatus (OECD 201, read across)

Key value for chemical safety assessment

EC50 for freshwater algae:
32.56 mg/L
EC10 or NOEC for freshwater algae:
11.25 mg/L

Additional information

No studies investigating the toxicity to aquatic algae of Sodium hydrogen N-(1-oxododecyl)-L-glutamate (CAS No. 29923-31-7) are available. Thus, available data for the source substance l-Glutamic acid, N-coco acyl derivs., monosodium salts (CAS No. 68187-32-6) was used in a read-across approach. The read across is considered valid asthe target substance is the major component, and the central member of an homologous series of components, of the source substances, possessing identical functional groups and extremely similar structures.  It is reasonable to expect that the toxicological properties of the target and source substances will not be markedly different.  On this basis, experimental data on the source substances are expected to be directly applicable to the target substance, and can be used to adequately predict its properties. Further details are provided in the in the field “Attached documents” The read across key study was performed according to GLP and OECD guideline 201 using Scenedesmus subspicatus as test organism (Cognis, 2001). A 29.6 % solution of the substance in water was tested. Nominal concentrations between 3.53 and 400 mg/L (based on test material) were tested over a period of 72 h. The 72h-EC50 (based on active matter) is determined to be 32.56 mg/L and the 72h-NOEC is determined to be 11.25 mg/L. Due to the rational provided above for the read-across approach, this result can also be considered for Sodium hydrogen N-(1-oxododecyl)-L-glutamate (CAS No. 29923-31-7).