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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

EC50 (48h) = 49 mg/L (measured) for Daphnia magna (OECD 202, read across)

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
49 mg/L

Additional information

No studies investigating the toxicity to aquatic invertebrates of Sodium hydrogen N-(1-oxododecyl)-L-glutamate (CAS No. 29923-31-7) are available. Thus, available data for the source substance l-Glutamic acid, N-coco acyl derivs., monosodium salts (CAS No. 68187-32-6) was used in a read-across approach. The read across is considered valid asthe target substance is the major component, and the central member of an homologous series of components, of the source substances, possessing identical functional groups and extremely similar structures.  It is reasonable to expect that the toxicological properties of the target and source substances will not be markedly different.  On this basis, experimental data on the source substances are expected to be directly applicable to the target substance, and can be used to adequately predict its properties. Further details are provided in the in the field “Attached documents”.

The read across key study was performed according to GLP and OECD guideline 202 using Daphnia magna as test organism (Laus, 2011). Nominal concentrations between 2.2 and 100 mg/L were tested over a period of 48 h. Thus, a 48h-EC50 is determined to be 49 mg/L based on the measured test concentration. Due to the rational provided above for the read-across approach, this result can also be considered for Sodium hydrogen N-(1-oxododecyl)-L-glutamate (CAS No. 29923-31-7)