Registration Dossier
Registration Dossier
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EC number: 249-958-3 | CAS number: 29923-31-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC10 (3h) > 1000 mg/L (nominal, based on active matter) for activated sludge (OECD 209)
Key value for chemical safety assessment
Additional information
No studies investigating the toxicity to aquatic microorganisms of Sodium hydrogen N-(1-oxododecyl)-L-glutamate
(CAS No. 29923-31-7) are available. Thus, available data for the source substance l-Glutamic acid, N-coco acyl derivs., disodium salts (CAS No. 68187-30-4) was used in a read-across approach. The read across is considered valid asthe target substance is the major component, and the central member of an homologous series of components, of the source substances, possessing identical functional groups and extremely similar structures. It is reasonable to expect that the toxicological properties of the target and source substances will not be markedly different. On this basis, experimental data on the source substances are expected to be directly applicable to the target substance, and can be used to adequately predict its properties. Further details are provided in the in the field “Attached documents”.The read across Key study was performed according to GLP and OECD guideline 209 using non-adapted activated sludge as inoculum (BASF, 2012). Nominal concentrations between 118 and 1887 mg/L were tested, which correspond to test concentrations of 62.5 to 1000 mg/L based on active matter. No respiration inhibition compared to the control was observed in any treatment. Thus, a 3h-EC10 (based on active matter) is determined to be > 1000 mg/L. Due to the rational provided above for the read-across approach, this result can also be considered for Sodium hydrogen N-(1-oxododecyl)-L-glutamate (CAS No. 29923-31-7).
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