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EC number: 202-430-6
CAS number: 95-54-5
The percutaneous absorption of p-PDA, 2-nitro-p-PDA, 2
-amino-4 -nitrophenol, 4 -chloro-m-phenylenediamine, and 4 -amino-2
-nitrophenol were also tested in this study. The octanol/water partition
coefficients were generally in the same rank order as the permeability
constants. Preliminary stratum corneum/water partition studies resulted
in values that were in the reverse order of skin permeation. When
binding of the compounds to components of the membrane were saturated,
the partition values more closely duplicated the rank order of
permeability of dyes.
Percutaneous Absorption of Hair dyes
Octanol/water partition coefficient
Stratum corneum/water partition coefficient
Permeability constant cm/h
Dependence of Km on Concentration of o-phenylenediamine
(M x 105)
Bound (M x 104)
Free (M x 105)
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