Registration Dossier
Registration Dossier
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EC number: 202-430-6 | CAS number: 95-54-5
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
The 96-hour LC50 for fish, the 48-hour EC50 for crustacea, and the 96-hour ErC50 for algae are 42.9, 1.4, and 0.16 mg/L, respectively. The 21-day NOEC (reproduction) in Daphnia is 0.08 mg/L. Additionally, the substance is considered not rapidly degradable. Based on all the available data, the test substance is classified as Acute Cat 1 (H400: Very toxic to aquatic life) and Chronic Cat 1 (H410: Very toxic to aquatic life with long lasting effects) according to EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008. The existing classification for Annex VI was Category 1 for acute and chronic aquatic toxicity.
In accordance with article 10 of the CLP Regulation (EC) No 1272/2008, if an M-factor is not yet given in Part 3 of Annex VI to the CLP Regulation, an M-factor should be determined and a scientific justification provided, when classifying substances for Acute Category 1 or Chronic Category 1. For this substance, adequate acute aquatic data are available in fish, aquatic invertebrates, and algae. An Acute M-Factor is based on the lowest reported effects in the most sensitive species, algae. Therefore, the M factor is 1 based on the 96 h EC/LC50 of 0.16 mg/L in algae.
In accordance with article 10 of the CLP Regulation (EC) No 1272/2008, if an M-factor is not yet given in Part 3 of Annex VI to the CLP Regulation, an M-factor should be determined and a scientific justification provided, when classifying substances for Acute Category 1 or Chronic Category 1. For this substance, chronic data were available in invertebrates; acute data were also available. However, the chronic data drive the classification. The lowest reported effects in chronic data were the 21 d NOEC data of 0.08 mg/L in aquatic invertebrate. The test substance is Not biodegradable. Therefore, the M factor is 1.
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