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Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature
Remarks:
Secondary source reviewed, original document not reviewed

Data source

Reference
Reference Type:
secondary source
Title:
Allergies to aromatic amino and nitro compounds.
Author:
Schulz, K.H.
Year:
1962
Bibliographic source:
Berufsdermatosen, 10:69-91 (cited in IUCLID (2000). IUCLID Dataset "o-phenylenediamine" (February 19)).

Materials and methods

Study type:
case report
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
o-phenylenediamine
EC Number:
202-430-6
EC Name:
o-phenylenediamine
Cas Number:
95-54-5
Molecular formula:
C6H8N2
IUPAC Name:
benzene-1,2-diamine

Results and discussion

Results of examinations:
positive reaction in 3 patients as a result of a group sensitization to aromatic amino and nitro compounds

Applicant's summary and conclusion

Conclusions:
sensitising
Executive summary:

Positive reaction was observed in 3 patients as a result of a group sensitization to aromatic amino and nitro compounds.