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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1940
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Information from peer reviewed reference.

Data source

Reference
Reference Type:
publication
Title:
FURTHER STUIDES ON THE BEHAVIOR OF GLUCONIC ACID AND AMMONIUM GLUCONATE IN ANIMALS AND MAN
Author:
Chenoweth M, Civin H, Salzman C, Cohn M, & Gold H
Year:
1940
Bibliographic source:
The Journal of Laboratory and Clinical Medicine Vol 26
Report date:
1940

Materials and methods

Type of study / information:
Pharmacology of gluconic acid in cats following oral administration.
Test guideline
Qualifier:
no guideline available
GLP compliance:
no
Remarks:
Study pre-dates GLP

Test material

Constituent 1
Chemical structure
Reference substance name:
D-gluconic acid
EC Number:
208-401-4
EC Name:
D-gluconic acid
Cas Number:
526-95-4
Molecular formula:
C6H12O7
IUPAC Name:
D-gluconic acid
Details on test material:
- Name of test material (as cited in study report): gluconic acid

Results and discussion

Any other information on results incl. tables

The general appearance of the cats remained unchanged and they retained their control weight. Three developed vomiting and diarrhea on several occasions. The urine remained unchanged. There were no significant findings from gross or histopathologic examination.

Applicant's summary and conclusion