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EC number: 630-473-4 | CAS number: 14595-54-1
In an acute oral toxicity study (limit test) performed according to OECD Guideline No. 401 and in compliance with GLP, group (5/sex/dose) of Sprague-Dawley rats were given a single oral (gavage) dose of test material at 2000 mg/kg bw. Animals were then observed for mortality, clinical signs and bodyweights for 14 days and at the end of the study the surviving animals were sacrificed for macroscopic examination.
No mortality or clinical signs were observed. Surviving animals showed expected gains in bodyweight over the 14-day study period. No abnormalities were noted at necropsy of animals that were killed at the end of the study.
Oral LD50 Combined > 2000 mg/kg bw.
Under the test conditions, the test material is not classified for acute oral toxicity according to the annex VI of the Regulation EC No. 1272/2008 (CLP) and to the GHS.
This study is considered as acceptable and satisfies the requirement for acute oral toxicity endpoint.
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