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EC number: 630-473-4
CAS number: 14595-54-1
an acute oral toxicity study (limit test) performed according to OECD
Guideline No. 401 and in compliance with GLP, group (5/sex/dose) of
Sprague-Dawley rats were given a single oral (gavage) dose of test
material at 2000 mg/kg bw. Animals were then observed for mortality,
clinical signs and bodyweights for 14 days and at the end of the study
the surviving animals were sacrificed for macroscopic examination.
mortality or clinical signs were observed. Surviving animals showed
expected gains in bodyweight over the 14-day study period. No
abnormalities were noted at necropsy of animals that were killed at the
end of the study.
LD50 Combined > 2000 mg/kg bw.
the test conditions, the test material is not classified for acute oral
toxicity according to the annex VI of the Regulation EC No. 1272/2008
(CLP) and to the GHS.
study is considered as acceptable and satisfies the requirement for
acute oral toxicity endpoint.
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