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Physical & Chemical properties

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Description of key information

Appearance:

On the basis of visual perceptual/Olfactory property,the chemical 2-ethoxy benzoic acid was observed to be colourless liquid in appearance.

Freezing point:

The Freezing point determination of 2-ethoxy benzoic acid (pure)(CAS No. 134-11-2) was done using crushed ice and salt.. The determination was done on the basis of cooling curve (time vs temperature) obtained when the substance was placed in the cooling bath. The freezing point was determined to be 10.78°C at 976.4 hPa.

Boiling point:

The boiling point determination of 2-ethoxy benzoic acid (pure) (CAS No. 134-11-2) was done following OECD Guideline 103 and according to the method of Siwoloboff. The test was conducted in replicates and mean boiling point was determined to be 262.9°C at 976.8 hPa.

Density:

The density of  2-ethoxy benzoic acid (pure) (CAS No. 134-11-2)was determined following OECD Guideline 109 and according to the IS 4730 : 1994 (Reaffirmed 2010) – Method for Determination of Density of Liquids (First Revision) using glass pyknometer. The mean density of test item is was determined to be 0.9754 g/cm³ at 20°C and 976.9 hPa

Particle Size Distribution:

The study does not need to be conducted because the test chemical is marketed or used in a non- solid or granular form.

Vapour Pressure:

Data from authoritative and modeling databases suggests that the estimated vapour pressure of 2-Ethoxybenzoic acid at 25 deg C was 0.00211 mmHg = 0.281 Pa

Partition Coefficient:

Based on the available data from study report,the partition Coefficient n-octanol/water of test chemical 2-ethoxy benzoic acid (CAS No. 134-11-2) was determined by the Reverse Phase High Performance Liquid Chromatographic method according to OECD Guideline No. 117 for testing of Chemicals. A test item solution was prepared by accurately pipetting 4 microliter of test item and diluted with Acetonitrile up to 10 ml. Thus, the test solution concentration was 390 mg/l. The pH of test substance was 6.1. The reference substances were chosen according to functionally similarity with the test substance and calibration graph was prepared. The reference substances were 4-Acetylpyridine, Biphenyl, Diphenylamine, Dodecanoic acid, Naphthalene, n-Butylbenzene having Pow value ranging from 0.5 to 4.6. The Log Pow value of the test chemical 2-ethoxy benzoic acid was determined to be 1.295 ± 0.008 dimensionless at 25°C. On the basis of this value, test chemical 2-ethoxy benzoic acid can be considered to be hydrophilic in nature.

Water Solubility:

The water solubility determination of test item 2-ethoxy benzoic acid (pure) (CAS No. 134-11-2) was done as per the OECD guideline 105 by spectrophotometric analytical method as per OECD 101. The solubility of (2-ethoxy benzoic acid (pure) of CAS No: 134-11-2 )in water was determine to be 7839 mg/L at 25°C.

Thus test chemical is considered to be soluble in water.

Surface tension:

From available data of chemspider database, the surface tension of 2-ethoxybenzoic acid (134-11-2) was predicted to be 43.5 mN/m.

Flash point:

From laboratory data the flash point determination of 2-ethoxy benzoic acid (pure) (CAS No. 134-11-2) was done following closed cup method using Pensky-Martens flash point apparatus. The test was conducted in replicates and mean flash point was determine to be 98.6°C at 977.1hPa.

Autoflammability:

2-ethoxybenzoic acid did not catch fire on being exposed to air at room temperature of 27°C and atmospheric pressure of 966 hPa. This indicates that 2-ethoxybenzoic acid is not auto-flammable.

Flammability:

2-ethoxybenzoic acid does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 2-ethoxybenzoic acid is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 2-ethoxybenzoic acid was considered non-flammable.

Explosiveness:

The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties

Oxidising properties:

The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied

pH:

The pH determination of test item 2-ethoxy benzoic acid (pure) (CAS No 134-11-2) was done following OECD guideline 122. pH of 1% w/v emulsion was measured with the help of pH meter and it was observed to be 2.50 at 26 °C. This indicate the 2 ethoxybenzoic acid was acidic in nature.

Viscosity:

The viscosity determination of substance 2-ethoxy benzoic acid (pure) (CAS No. 134-11-2 )was done as per the test guideline OECD 114 using Redwood Viscometer No. 1. Kinematic viscosity (experimental) of substance at 30°C and 50°C is 68.32 mm²/sec and 25.67 mm²/s, respectively. Dynamic viscosity (calculated) of Test item at 30°C and 50°C is 66.63 mPa.S and 25.12 mPa.S, respectively

Additional information

Appearance:

On the basis of visual perceptual/Olfactory property,the chemical 2-ethoxy benzoic acid was observed to be colourless liquid in appearance.

Freezing point:

The Freezing point determination of 2-ethoxy benzoic acid (pure)(CAS No. 134-11-2) was done using crushed ice and salt.. The determination was done on the basis of cooling curve (time vs temperature) obtained when the substance was placed in the cooling bath. The freezing point was determined to be 10.78°C at 976.4 hPa.

Other supporting studies from reliabe sources such as authoritative database and handbooks suggests that freezing point of chemical 2-ethoxy benzoic acid was determined to be in the range of 19.4 degree C to 20.7 degree C.

As the data from lab has K1 reliability and the test was performed using standard methods of analysis which has the value of freezing point as 10.78 degree C,thus considered as key study for the chemical safety assessment

Boiling point:

The boiling point determination of 2-ethoxy benzoic acid (pure) (CAS No. 134-11-2) was done following OECD Guideline 103 and according to the method of Siwoloboff. The test was conducted in replicates and mean boiling point was determined to be 262.9°C at 976.8 hPa.

Other supporting study from reliable handbook suggests that the boiling point of chemical 2-ethoxy benzoic acid was 211 degree C.

As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of boiling point temperature as 262.9 degree C thus considered as key study for the chemical safety assessment.

Density:

The density of  2-ethoxy benzoic acid (pure) (CAS No. 134-11-2)was determined following OECD Guideline 109 and according to the IS 4730 : 1994 (Reaffirmed 2010) – Method for Determination of Density of Liquids (First Revision) using glass pyknometer. The mean density of test item is was determined to be 0.9754 g/cm³ at 20°C and 976.9 hPa.

Other supporting study reliable handbook ,the density of chemical 2-ethoxy benzoic acid was reported to be 1.105 g/cm3.

As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of density as 0.9754 g/cm3 at 20 degree C thus considered as key study for the chemical safety assessment

Particle Size Distribution:

The study does not need to be conducted because the test chemical is marketed or used in a non- solid or granular form.

Vapour Pressure:

Data from authoritative and modeling databases suggests that the estimated vapour pressure of 2-Ethoxybenzoic acid at 25 deg C was 0.00211 mmHg = 0.281 Pa

Partition Coefficient:

Based on the available data in a key study from study report, the partition Coefficient n-octanol/water of test chemical 2-ethoxy benzoic acid (CAS No. 134-11-2) was determined by the Reverse Phase High Performance Liquid Chromatographic method according to OECD Guideline No. 117 for testing of Chemicals. A test item solution was prepared by accurately pipetting 4 microliter of test item and diluted with Acetonitrile up to 10 ml. Thus, the test solution concentration was 390 mg/l. The pH of test substance was 6.1. The reference substances were chosen according to functionally similarity with the test substance and calibration graph was prepared. The reference substances were 4-Acetylpyridine, Biphenyl, Diphenylamine, Dodecanoic acid, Naphthalene, n-Butylbenzene having Pow value ranging from 0.5 to 4.6. The Log Pow value of the test chemical 2-ethoxy benzoic acid was determined to be 1.295 ± 0.008 dimensionless at 25°C.

Additional study from authoritative and modelling database indicates that the octanol waterpartition coefficient (log Pow) value of the test chemical 2-ethoxy benzoic acid was estimated to be 2.1.

Thus, based on the available information, the logPow valueof the test chemical 2-ethoxy benzoic acid ranges from 1.29 to 2.1, respectively. On the basis of this value, chemical 2-ethoxy benzoic acid can be considered to be hydrophilic in nature.

Water Solubility:

The water solubility determination of test item 2-ethoxy benzoic acid (pure) (CAS No. 134-11-2) was done as per the OECD guideline 105 by spectrophotometric analytical method as per OECD 101. The solubility of (2-ethoxy benzoic acid (pure) of CAS No: 134-11-2 )in water was determine to be 7839 mg/L at 25°C.

Thus test chemical is considered to be soluble in water.

Surface tension:

From available data of chemspider database, the surface tension of 2-ethoxybenzoic acid (134-11-2) was predicted to be 43.5 mN/m.

Flash point:

Various predicted studies for the benzyl 2-ethoxybenzoic acid (134-11-2) were reviewed to summarize the following information:

From laboratory data the flash point determination of 2-ethoxy benzoic acid (pure) (CAS No. 134-11-2) was done following closed cup method using Pensky-Martens flash point apparatus. The test was conducted in replicates and mean flash point was determine to be 98.6°C at 977.1hPa.

From available data of handbook, the flash point of 2-ethoxybenzoic acid (134-11-2) was determined to be >110 degree C. Based on criteria mentioned in CLP regulation the chemical has flash point >than 60 degree C hence the 2-ethoxybenzoic acid (134-11 -2) was considered to be non-flammable.

As the data from laboratory report has K1 reliability and the test was performed using OECD guidelines which has the value of flash point as 98.6 °C at977.1 hPathus considered as key study for the chemical safety assessment. Also based on criteria mentioned in CLP regulation the chemical has flash point >than 60 degree C hence the benzyl 2-ethoxybenzoic acid (134-11-2) was considered to be non-flammable.

Autoflammability:

2-ethoxybenzoic acid did not catch fire on being exposed to air at room temperature of 27°C and atmospheric pressure of 966 hPa. This indicates that 2-ethoxybenzoic acid is not auto-flammable.

Flammability:

2-ethoxybenzoic acid does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 2-ethoxybenzoic acid is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 2-ethoxybenzoic acid was considered non-flammable.

Explosiveness:

The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties

Oxidising properties:

The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied

pH:

The pH determination of test item 2-ethoxy benzoic acid (pure) (CAS No 134-11-2) was done following OECD guideline 122. pH of 1% w/v emulsion was measured with the help of pH meter and it was observed to be 2.50 at 26 °C. This indicate the 2 ethoxybenzoic acid was acidic in nature.

Viscosity:

The viscosity determination of substance 2-ethoxy benzoic acid (pure) (CAS No. 134-11-2 )was done as per the test guideline OECD 114 using Redwood Viscometer No. 1. Kinematic viscosity (experimental) of substance at 30°C and 50°C is 68.32 mm²/sec and 25.67 mm²/s, respectively. Dynamic viscosity (calculated) of Test item at 30°C and 50°C is 66.63 mPa.S and 25.12 mPa.S, respectively.