Registration Dossier
Registration Dossier
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EC number: 277-554-7 | CAS number: 73612-40-5
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
LC0 (96 h), Zebrafish)=13mg/L
LC50 (96h, Zebrafish)= )=4.62 mg/L
LC100 (96h, Zebrafish)=10 mg/L
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 4.62 mg/L
Additional information
The substance was tested for its acute toxicity to fish (Rainbow trout, RedKilli fish, Zebrafish) according to the A-11 method, comparable to today’s OECD203 standard testing procedure published by the OECD.
Based on the weight of evidence approach, the LC50 range, collected from several available studies on the substance itself, is 0.63-6.3 mg/L.
However, based on the time of the exposure of the available studies, only one study can be considered with Klimish 2.
As a matter of fact, the LC50s of the fours studies were calculated at 48h instead of the 96 hours, as indicated into the OECD Guideline. The reliable 2 study reports an LC50 at 96 hours, on Zebrafish, of 4.62 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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