Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-346-4 | CAS number: 57-68-1
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 Daphnia magna 48h for Sulfadimidine = 31.4 mg/l
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 31.4 mg/L
Additional information
Some data regarding short-term toxicity to aquatic invertebrates are reported in database ECOTOX, EPA for Sulfadimidine CAS 57-68-1:
- EC50 Daphnia magna 48h = values 31.4, 39, 109.5 and 185.3 base on different light source used (ref. Jung et all, Ecotoxicology 17(1): 37-45, 2008. Specific experimental condition are explained in the abstract free available on website https://www.ncbi.nlm.nih.gov/pubmed/17940867 : The lighting conditions were as follows: (1) fluorescent light only, (2) continuous irradiation with 15 microW/cm(2) UVB, (3) pulsed irradiation with 90 microW/cm(2) UVB for 4 h/d, and (4) natural sunlight (outdoors). Laboratory tests showed that phototoxicity resulting from exposure to continuous UVB light generally increased the acute toxicity of the sulfonamides in Daphnia magna.)
- EC50 Daphnia magna 48h = 174.4 mg/l (ref. Kim et all, Environ. Int.33(3): 370-375, 2007)
- EC50 Daphnia magna 48h = 202 mg/l (ref. De Liguoro, Chemosphere75(11): 1519-1524, 2009)
- EC50 Daphnia magna 48h = 215.9 mg/l (ref. Park et all, Ecotoxicology17(6): 526-538, 2008)
According to the CLP Regulation (EC n.1272/2008) the data of short-term toxicity to aquatic invertebrates for Sulfadimidine are of no concern for acute aquatic toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
