Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-346-4 | CAS number: 57-68-1
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
In the human body Sulfadimidine is excreted in the urine in 2 days, 70% being in the form of the acetyl derivative.
Key value for chemical safety assessment
Additional information
As reported in HSDB Report of Sulfamethazine (synonym of Sulfadimidine) with reference to Reynolds, The Extra Pharmacopoeia. 28th ed. p. 1476, 1982 Sulfadimidine is readily absorbed from the gastrointestinal tract and about 60 to 80% is bound to plasma albumin. After 330 mg oral administration the half life is 2.3 h. In the human body Sulfadimidine is excreted in the urine in 2 days, 70% being in the form of the acetyl derivative.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
