Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report Date:
2016

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline
Specific details on test material used for the study:
Manufacturer: Anhui Shindo Chemical CO. LTDSupplier: Changzou Foreign Trade Corp.Batch number: 0102A26 (20151203)Physical state: Solid, crystalline substanceColour: WhiteStorage: in a cool, dry

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
1.8
Temp.:
30 °C
pH:
7.86

Applicant's summary and conclusion

Conclusions:
The estimated mean logPow of Amidinothiourea is 1.8