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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

LC50(96 h) = 4.44 mg a.i./L (Danio rerio, OECD 203, nominal, read-across to EC 931-700-2)

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
4.44 mg/L

Additional information

As no acute study is available for assessing the toxicity of the substance on fish, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 Grouping of substances, a read-across to the structurally related Alkyl Dimethyl betaine (EC-No. 931-700-2) was applied. The read across is justified due to the structural similarity of the analogue substances and similar physico-chemical properties resulting in a similar environmental fate and ecotoxicity profile. Further justification is given in the analogue justification attached to section 13 in IUCLID.

One key GLP study was conducted according to OECD guideline 203 using Brachidanio (Danio) rerio (Jung, 1989). Fish were exposed for 96 h to 4 test concentrations under static condictions. Mortality was assessed and revealed a LC 50 (96h) of 14.8 mg/L for the test substance in aqueous solution (30% in water) and a LC50 (96h) of 4.44 mg a.i./L.