Registration Dossier
Registration Dossier
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EC number: 939-682-8 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (96 h) for Daphnia magna = 5.3 mg a.i./L (nominal, OECD 202).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 5.3 mg/L
Additional information
As no acute study is available for assessing the toxicity of the substance on aquatic invertebrates, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 Grouping of substances, a read-across to the structurally related Alkyl Dimethyl betaine (EC-No. 931-700-2) and pure homologues (alkyl betaine C10, C12, C14) was applied. The read across is justified due to the structural similarity of the analogue substances and similar physico-chemical properties resulting in a similar environmental fate and ecotoxicity profile. Further justification is given in the analogue justification attached to section 13 in IUCLID.
The two studies were conducted according to OECD 202. Garcia (2008) revealed EC50 (72 h) values between 5.3 (C12-Betaine, pure) and 48 mg/L (C10-Betaine, pure), depending on the chain lengh. In the test conducted with 100% substance of EC-No. 931-700-2 an EC50 value of 7.76 mg/L was found (Vandendaele, 2010).
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