Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Decades of experience handling saturated perfluorocarbons have indicated no toxic effects for any of these substances, which has been confirmed by skin sensitisation testing by contract laboratories including HRC, SRI Int, Safepharm and Toxicol on representive substances from the class. Their use in medical applications in the blood, lungs and eyes further supports the data.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)

Justification for classification or non-classification

Decades of experience handling saturated perfluorocarbons have indicated no toxic effects for any of these substances, although no respiratory sensitisation testing has been conducted by contract laboratories that we are aware of. Their use in medical applications in the blood, lungs and eyes supports the data.