Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Effects on fertility

Effect on fertility: via oral route
Endpoint conclusion:
no study available
Effect on fertility: via inhalation route
Endpoint conclusion:
no study available
Effect on fertility: via dermal route
Endpoint conclusion:
no study available
Additional information

Reproductive toxicity is not considered to be of concern in the industrial environment where stringent risk mitigation measures are routinely incorporated into operational procedures. As a result, and in line with the ECHA news alert ‘Clarity on interface between REACH and the Cosmetics Regulation’ of 27 October 2014, where registrants are permitted to perform animal testing to meet the human health information requirements of REACH only when there is a need to assess worker safety, it is considered inappropriate to carry out further investigations involving vertebrate animals.


Short description of key information:
No evidence of toxicity has been reported as the result of acute testing, the neat test item is used exclusively as a cosmetic ingredient, the substance has been declared as safe for use in cosmetics by the Cosmetic Ingredient Review Expert Panel and further tests involving vertebrate animals are inappropriate.

Effects on developmental toxicity

Description of key information
No evidence of toxicity has been reported as the result of acute testing, the neat test item is used exclusively as a cosmetic ingredient, the substance has been declared as safe for use in cosmetics by the Cosmetic Ingredient Review Expert Panel and further tests involving vertebrate animals are inappropriate.
Effect on developmental toxicity: via oral route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via inhalation route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via dermal route
Endpoint conclusion:
no study available
Additional information

Developmental toxicity is not considered to be of concern in the industrial environment where stringent risk mitigation measures are routinely incorporated into operational procedures. As a result, and in line with the ECHA news alert ‘Clarity on interface between REACH and the Cosmetics Regulation’ of 27 October 2014, where registrants are permitted to perform animal testing to meet the human health information requirements of REACH only when there is a need to assess worker safety, it is considered inappropriate to carry out further investigations involving vertebrate animals.

Justification for classification or non-classification

No evidence of toxicity has been reported as the result of acute testing, the neat test item is used exclusively as a cosmetic ingredient, and the substance has been declared as safe for use in cosmetics by the Cosmetic Ingredient Review Expert Panel. Moreover, ECHA news alert ‘Clarity on interface between REACH and the Cosmetics Regulation’ of 27 October 2014, states that registrants are permitted to perform animal testing to meet the human health information requirements of REACH only when there is a need to assess worker safety, and it is considered inappropriate to carry out further investigations involving vertebrate animals. Reproductive and developmental toxicity are not considered to be of concern in the industrial setting where stringent risk mitigation measures are routinely incorporated into operational procedures and classification under the terms of Regulation (EC) No. 1272/2008 is not required.

Additional information