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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
21 August 2015 to 11 September 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study performed in accordance with OECD, EU & US EPA test guidelines in compliance with GLP and reported with a valid GLP certificate.
Reason / purpose:
reference to same study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
other: differential scanning calorimetry (DSC).
Melting / freezing pt.:
50 °C
Atm. press.:
1 013.25 hPa
Decomposition:
no
Sublimation:
no

An endothermic peak between 25°C and 75°C was observed. The extrapolated onset temperature of the peak could not be determined since it was observed within 2 minutes from the start of the experiment. The effect was most likely obtained due to melting of the test item.

To investigate the melting peak between 25°C and 75°C a repeated heating cycle was applied in the Experiment 2. The experiment also started at a lower temperature in order to determine the extrapolated onset temperature of the melting peak. With the first heating the extrapolated onset temperature of the melting peak was 50.07°C.

During cooling an exothermic peak was observed between 30°C and 50°C (results are archived in the raw data). The effect was obtained due to crystallization of the test item.

With the second heating an extrapolated onset temperature of 47.94°C was obtained. The extrapolated onset was not used for calculation of the melting temperature, since it was obtained by melting of non-original test substance. The results demonstrated that the endothermic effect was due to melting of the test item. After the experiment, a white molten residue remained in the sample container.

Experiment 3 was performed to determine the duplicate melting temperature of the test item.

The extrapolated onset of the melting peak was 50.05°C. After the experiment, a white molten residue remained in the sample container.

The melting temperature was determined as the average melting temperature obtained from experiment 2 (50.07°C) and experiment 3 (50.05°C).

Conclusions:
The melting temperature of 2,2-Bis[[3-(dodecylthio)-1-oxopropoxy]methyl]propane-1,3-diyl bis[3-(dodecylthio)propionate] was determined at 50°C (323K) by using DSC.
Executive summary:

The melting temperature of the test item was determined using differential scanning calorimetry (DSC).

 

The study was performed in accordance with the following guidelines:

European Community (EC), EC no. 440/2008, Part A: Methods for the Determination of Physico-

Chemical Properties, Guideline A.1: “Melting/Freezing Temperature”, Official Journal of the European Union no. L142, May 31, 2008.

Organization for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals no. 102: "Melting Point / Melting Range", July 27, 1995.

United States Environmental Protection Agency (EPA), Product Properties Test Guidelines no. OPPTS 830.7200: "Melting Point/Melting Range", March 1998.

 

The melting temperature is defined as the temperature at which the phase transition from solid to liquid state takes place at normal atmospheric pressure. This temperature ideally corresponds to the solidification or freezing temperature.

 

The melting temperature of 2,2-Bis[[3-(dodecylthio)-1-oxopropoxy]methyl]propane-1,3-diyl bis[3-(dodecylthio)propionate] was determined at 50°C (323K) by using DSC.

Description of key information

Key value determined in GLP accredited laboratory study using DSC and performed in accordance with OECD Guideline 102, EU Method A.1 and US EPA Procedure 830.7200

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
50 °C

Additional information

The melting temperature of the test item was determined using differential scanning calorimetry (DSC).

 

The melting temperature is defined as the temperature at which the phase transition from solid to liquid state takes place at normal atmospheric pressure. This temperature ideally corresponds to the solidification or freezing temperature.

 

The melting temperature of 2,2-Bis[[3-(dodecylthio)-1-oxopropoxy]methyl]propane-1,3-diyl bis[3-(dodecylthio)propionate] was determined at 50°C (323K) by using DSC.