Registration Dossier
Registration Dossier
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EC number: 297-566-6 | CAS number: 93642-68-3
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Short-term toxicity to fish: 96 hr EC50 >100 mg/l (nominal, supported by analysis) (highest concentration tested) (OECD 203).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
A 96-h LC50 value of >100 mg/l and NOEC of >=100 mg/l (nominal, supported by analysis) (highest concentration tested) have been determined for the effects of the registration substance on mortality of Zebra fish (Brachydanio rerio).
In view of the test media preparation method and static exposure regime it is likely that the test organisms were exposed predominantly to a mixture of: the parent substance, its butanedioic acid- containing hydrolysis products, silanol hydrolysis products and potentially cross-linked by-products, and ethanol. Dissolved complexes of chemical structures containing the butanedioate group are also likely.
It is noted that other studies have consistently reported formation of white solid precipitates even at loadings as low as 1 mg/l. This study does not report any observation of precipitates. It is unclear how such high concentrations were achieved in this study. It is possible that the test medium was a dispersion rather than a true solution or used test media with particularly low mineral concentrations.
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