Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 282-775-7 | CAS number: 84418-63-3
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The PBT Assessment for 3,5,5 trimethylhexanoic acid, mixed esters with dipentaerythritol (CAS 84418-63-3) is based on the criteria set out in the “Guidance on information requirements and chemical safety assessment, Chapter R.11: PBT Assessment” (ECHA, 2014).
Persistence: vP
One study with the structurally closely related read across substance 3,5,5-trimethylhexanoic acid hexaester with dipentaerythritol (CAS 84418-63-3) according to OECD 301B resulted in 4.3% (CO2 evolution) degradation after 60 d. Thus, according to the definite criteria set out in Annex XIII of Regulation (EC) No 1907/2006 3,5,5 trimethylhexanoic acid, mixed esters with dipentaerythritol (CAS 84418-63-3) is considered to be very persistent (vP).
Bioaccumulation: not B
3,5,5 trimethylhexanoic acid, mixed esters with dipentaerythritol (CAS 84418-63-3) is characterized by a low water solubility (< 10 µg/L), high log Kow (> 10) and high molecular weights (> 800 g/mol). Based on the physico/chemical properties such as low water solubility and high potential for adsorption a reduced availability in water is expected. The high molecular weight of the substance significantly reduces the absorption due to sterical hindrance to cross biological membranes. It can be concluded that the log Kow indicating a potential for bioaccumulation, overestimates the true bioaccumulation potential of the substance. BCF/BAF values estimated by QSAR (BCFBAF v3.01) also indicate that the substance will not be bioaccumulative (all well below 2000 L/kg). Taking all these information into account, it can be concluded that bioaccumulation of 3,5,5 trimethylhexanoic acid, mixed esters with dipentaerythritol (CAS 84418-63-3) is unlikely to occur.
Toxicity: not T
All available data indicate no acute and chronic toxicity to aquatic organisms up to the limit of water solubility. Moreover, 3,5,5 trimethylhexanoic acid, mixed esters with dipentaerythritol (CAS 84418-63-3, UVCB) is not classified according to Directive 67/548/EEC and Regulation (EC) No. 1272/2008 (5th ATP). Thus, the criteria set out in Annex XIII of Regulation (EC) No 1907/2006 are not met and the test substance is not considered to meet the T criterion.
Conclusion
In conclusion the substance is not considered to meet the criteria to be classified as PBT or vPvB based on the available data.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
