Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 259-915-0 | CAS number: 55947-46-1
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
48 hrs aquatic toxicity study (SSS QSAR prediction model, 2016) was conducted to assess toxic effects of the test compound2-Propyne-1-sulfonic acid, sodium salt(CAS no 55947-46-1) . The predicted data suggests the effective concentration (EC50) for the test compound 2-Propyne-1-sulfonic acid, sodium salt was estimated to be256.680969238 mg/Lon the basis of mobility.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 256.681 mg/L
Additional information
Various predicted studies for the target chemical 2-Propyne-1-sulfonic acid, sodium salt and read across were reviewed to summarize the following information:
48 hrs aquatic toxicity study (SSS QSAR prediction model, 2016) was conducted to assess toxic effects of the test compound2-Propyne-1-sulfonic acid, sodium salt(CAS no 55947-46-1) and the results were predicted. The study was based on the effects of the test compound on the Daphnia magna in a static fresh water system. The predicted data suggests the effective concentration (EC50) for the test compound 2-Propyne-1-sulfonic acid, sodium salt was estimated to be256.680969238 mg/Lon the basis of mobility.
48 hrs aquatic toxicity study (EPI suite, 2016) was conducted to assess toxic effects of the test compound2-Propyne-1-sulfonic acid, sodium salt(CAS no 55947-46-1) and the results were predicted. The study was based on the effects of the test compound on Daphnia magna in a static fresh water system. The predicted data suggests the effective concentration (EC50) for the test compound2-Propyne-1-sulfonic acid, sodium saltwas estimated to be 181.6549 mg/l on the basis of mobility.
The short term toxicity to aquatic invertebrates was determined (P. Lundahl and R. Cabridenc,Water Research Vol. 12. pp. 25 to 30. 1978) to for 24 hrs as 6900 mg/l on the basis of 50% concentration immobilizing for read across substance Sodium butane-1-sulphonate. Concentration immobilizing 50% was determined by the technique of the A.F.N.O.R. for Daphnia magna.
The short term toxicity to aquatic invertebrates (Freeman,L.,Sewage Ind. Wastes 25(11): 1331-1335,1953) was study for 48 hrs for read across substance Sodium butane-1-sulphonate. As lake water was used as media. After experiment it was determined that the short term toxicity to aquatic invertebrates was determined to for 48 hrs as 8000 mg/l on the basis of mobility.
On the basis of results of various predictions, the chemical2-Propyne-1-sulfonic acid, sodium saltcan be considered as not likely to be toxic to aquatic invertebrates at environmentally relevant concentrations and can be classified as non- hazardous as per the criteria of CLP regulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
