Registration Dossier
Registration Dossier
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EC number: 217-090-4 | CAS number: 1738-25-6
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- other: review
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Aceeptable, well documented publication
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Lathyrism: A Neurotoxic Disease
- Author:
- Spencer P.S. and Schaumburg H.H.
- Year:
- 1 983
- Bibliographic source:
- Neurobehavioral Toxcicol. and Teratol., 5, 625-629 (1983)
Materials and methods
- Type of study / information:
- Review
- Principles of method if other than guideline:
- Review about the neurotoxic disease lathyrism and the causing agents.
- GLP compliance:
- no
Test material
- Reference substance name:
- 3-dimethylaminopropiononitrile
- EC Number:
- 217-090-4
- EC Name:
- 3-dimethylaminopropiononitrile
- Cas Number:
- 1738-25-6
- Molecular formula:
- C5H10N2
- IUPAC Name:
- 3-(dimethylamino)propanenitrile
Constituent 1
Results and discussion
Any other information on results incl. tables
There is no known relationship between lathyrism (caused by
excessive consumption of Lathyrus sativus) and the
neurodegenerative conditions associated with compounds like
beta-aminopropionitrile (contained in L. sativus), beta,
beta´-iminodipropionitrile and 3-dimethylaminopropionitrile
(both not contained in L. sativus).
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
