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Physical & Chemical properties

Partition coefficient

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Description of key information

The experimentally determined value for log Pow of quinidine is in a range of 2.84 - 3.71. 

Key value for chemical safety assessment

Log Kow (Log Pow):
2.84
at the temperature of:
25 °C

Additional information

The given log Pow of 2.84 measured at 25 °C is determined experimentally by using the potentiometric method. In the publication of Mannhold, 1990, the log Pow of 3.71 was experimentally determined. The log Pow of 3.44 is determined experimentally and available in EPI Suite v.4.11. and ChemIDplus Advanced. However, details on the method are not available. Therefore, we consider the log Pow of 2.84 as key value. The given log Pow of 2.84 indicates that quinidine is a lipophilic substance.