Registration Dossier
Registration Dossier
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EC number: 240-521-2 | CAS number: 16470-24-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
LC50 (96 h) Zebra fish > 1000 mg/l
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 1 000 mg/L
Additional information
Acute toxicity for Zebra fish was evaluated in the 96 hours screening test, according to the OECD guideline 203. Two concentrations were administrated at 562 and 1000 mg/l with no effect (Ciba - Geigy Ltd., 1992).
The study result is supported by other studies performed between 1973 and 1999 on Zebra fish at 96h for which only a summary is available indicating LC50 all greater than 1000 mg/l.
Furthermore, a prolonged semistatic assay over 14 days was conducted with Brachydanio rerio. Endpoints were mortality, signs of intoxication, length and weight. The nominal concentrations were 100, 316 and 1000 mg/l. There was no mortality and no difference in body weight at nominal concentrations of 100 and 316 mg/l. Only at 316 mg/l one fish showed slackening in movement (Bayer AG., 1992).
In conclusion, no fish acute toxicity is expected for the substance
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