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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Freshwater aquatic toxicity studies with Ethyltriglycol methacrylate were conducted in fish, daphnia, algal and microbial species.

Short-term toxicity to fish

One acute freshwater study in fish is available for Ethyltriglycol methacrylate, which is considered reliable with restriction (Klimisch score 2).

In a 48-h acute toxicity study according to DIN 38412, part 15, Golden orfe (Leuciscus idus melanotus) were exposed to Ethyltriglycol methacrylate under static conditions.  

The 48-h EC50was 406 mg/L (95% CL (confidence limit): 230 - 715 mg/L). Based on the results of this study, Ethyltriglycol methacrylate would be classified as non toxic to Leuciscus idus melanotus (fish) in accordance with the classification system of the EU-GHS.

Short-term toxicity to aquatic invertebrates

There are no short-term data available for aquatic invertebrates with Ethyltriglycol methacrylate but there is a long-term toxicity study to daphnia (21-day study, semi-static conditions according to OECD 211, Klimisch score 1, Evonik Industries AG, 2012).

In this vaild long-term guideline study for aquatic invertebrates (daphnids) Ethyltriglycol methacrylate has a NOEC of 100 mg/L (21-day, daphnia magna) based on mortality of adult daphnids. Therefore the short-term toxicity to daphnids EC50 (48 h) for Ethyltriglycol methacrylate is expected to be greater than 100 mg/L (based on mortality). For this reason there is no reason to perform a short-term toxicity test on aquatic invertebrates.

Toxicity to aquatic algae

One study in freshwater algae is available for Ethyltriglycol methacrylate, which is considered reliable without restriction (Klimisch score 1).

In a 72 hour acute toxicity study (static dose-response test), the cultures of Pseudokirchneriella subcapitata strain no. 61.81 SAG were exposed to Ethyltriglycol methacrylate at nominal concentrations of 0, 6.25, 12.5, 25, 50, and 100 mg/L under static conditions in accordance with the guideline OECD 201. The ErC50 value and the

ErC10 value based on growth rate was > 100 mg/L and EbC50 value based on yield was > 100 mg/L after 72 hours, respectively. The NOEC was 12.5 mg/L (72 h, growth rate and yield) and LOEC was 25 mg/L (72 h, growth rate and yield).

Long-term toxicity to fish

Long-term testing in fish is waived for Ethyltriglycol methacrylate since the substance is readily biodegradable. The risk characterisation shows that the PEC/PNECaqua ratio for the aquatic environment is <1, indicating no need for further information or testing. According to REACH regulationAnnex IX, 9.1. column 2, long-term toxicity testing shall only be considered when the chemical safety assessment indicates the need for further investigations. Thus, no long-term toxicity testing is required for Ethyltriglycol methacrylate.


Long-term toxicity to aquatic invertebrates

In a valid guideline study (OECD 211, semi-static conditions), the 21 day reproductive toxicity to daphnids was determined to be EC50: > 100 mg/L for Daphnia magna (STRAUS Clone 5), NOEC: 32 mg/L for the reproduction and 100 mg/L for the survival of the adult test animals. The EC10 21 d to daphnia magna (reproduction) of the substance Ethyltriglycol methacrylate was 77.1 mg/l. All effect values given are based on the geometric mean

measured test concentrations of Ethyltriglycol methacrylate. (Klimisch score: 1, Evonik Industries, 2013)

Toxicity to microorganisms

In accordance with column 2 of REACH Annex VIII, the activated sludge respiration inhibition test does not need to be conducted as this substance was found to be readily biodegradable in an OECD 301 F Manometric respiration test at an application concentration of 100 mg/L. There was no evidence for toxicity to bacteria. (Klimisch score : 2, for details of the study please see chapter: 5.2.1, Evonik Industries 1999)

Furthermore the toxicity of Ethyltriglycol methacrylate to microorganisms (Pseudomonas putida) was evaluated in bacteria toxicity test according to Bringmann-Kühn (modified DIN 38412, part 8) with limited documentation (Klimisch score: 4). The 16h-EC10 in this study was determined to be > 8000 mg/L for Ethyltriglycol methacrylate (for details of the study please see chapter: 6.1.7, Evonik Industries 1988).