Registration Dossier
Registration Dossier
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EC number: 254-588-0 | CAS number: 39670-09-2
Specific investigations: other studies
Administrative data
- Endpoint:
- cytotoxicity
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Test procedure in accordance with generally accepted scientific standards. Only abstract available.
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: XTT assay
- Principles of method if other than guideline:
- XTT assay with human gingival fibroblasts (HGF).
- GLP compliance:
- not specified
- Type of method:
- in vitro
Test material
- Reference substance name:
- 2-[2-(2-ethoxyethoxy)ethoxy]ethyl methacrylate
- EC Number:
- 254-588-0
- EC Name:
- 2-[2-(2-ethoxyethoxy)ethoxy]ethyl methacrylate
- Cas Number:
- 39670-09-2
- Molecular formula:
- C12H22O5
- IUPAC Name:
- 2-[2-(2-ethoxyethoxy)ethoxy]ethyl methacrylate
- Details on test material:
- - Substance: Ethyltriglycol methacrylate (ETMA)
- Purity: not specified, but commercial grade assumed
Constituent 1
Results and discussion
- Details on results:
- The Cytotoxic effect of Ethyltriglycol methacrylate on human gingival fibroblasts (HGF) was EC50 (half-maximum effect concentration): 12.000 mmol/L ((1.100 standard deviation) according to XTT assay.
Applicant's summary and conclusion
- Conclusions:
- The Cytotoxic effect of Ethyltriglycol methacrylate on human gingival fibroblasts (HGF) was EC50 (half-maximum effect concentration): 12.000 mmol/L ((1.100 standard deviation) according to XTT-based cell viability assay.
- Executive summary:
The Cytotoxic effect of Ethyltriglycol methacrylate on human gingival fibroblasts (HGF) was assessed XTT-based cell viability assay. Each experiment was performed at least four times. The EC50 for Ethyltriglycol methacrylate was determined to be 12.000 mmol/L ((1.100 standard deviation).
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