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EC number: 254-588-0
CAS number: 39670-09-2
aquatic toxicity studies with Ethyltriglycol methacrylate were conducted
in fish, daphnia, algal and microbial species.
toxicity to fish
freshwater study in fish is available for Ethyltriglycol methacrylate,
which is considered reliable with restriction (Klimisch score 2).
In a 48-h
acute toxicity study according to DIN 38412, part 15, Golden orfe
(Leuciscus idus melanotus) were exposed to Ethyltriglycol methacrylate
under static conditions.
toxicity to aquatic invertebrates
There are no
short-term data available for aquatic invertebrates with Ethyltriglycol
methacrylate but there is a long-term toxicity study to daphnia (21-day
study, semi-static conditions according to OECD 211, Klimisch score 1, Evonik
Industries AG, 2012).
to aquatic algae
One study in
freshwater algae is available for Ethyltriglycol methacrylate, which is
considered reliable without restriction (Klimisch score 1).
In a 72 hour acute toxicity study
(static dose-response test), the cultures of Pseudokirchneriella
subcapitata strain no. 61.81 SAG were exposed to Ethyltriglycol
methacrylate at nominal concentrations of 0, 6.25, 12.5, 25, 50, and
100 mg/L under static conditions in accordance with the guideline OECD
201. The ErC50 value and the
ErC10 value based on
growth rate was > 100 mg/L and EbC50 value based on yield
was > 100 mg/L after 72 hours, respectively. The NOEC was 12.5
mg/L (72 h, growth rate and yield) and LOEC was 25 mg/L (72 h,
growth rate and yield).
toxicity to fish
testing in fish is waived for Ethyltriglycol methacrylate since the
substance is readily biodegradable. The risk characterisation shows that
the PEC/PNECaqua ratio for the aquatic environment is <1, indicating no
need for further information or testing. According to REACH regulationAnnex
IX, 9.1. column 2, long-term toxicity testing shall only be considered
when the chemical safety assessment indicates the need for further
investigations. Thus, no long-term toxicity testing is required for
Long-term toxicity to aquatic
In a valid guideline study (OECD 211,
semi-static conditions), the 21 day reproductive toxicity to daphnids
was determined to be EC50: > 100 mg/L for Daphnia magna (STRAUS Clone
5), NOEC: 32 mg/L for the reproduction and 100 mg/L for the survival of
the adult test animals. The EC10 21 d to daphnia magna (reproduction) of
the substance Ethyltriglycol methacrylate was 77.1 mg/l.
All effect values given are based on the geometric mean
measured test concentrations of
(Klimisch score: 1, Evonik Industries, 2013)
Toxicity to microorganisms
In accordance with column 2 of REACH
Annex VIII, the activated sludge respiration inhibition test does not
need to be conducted as this substance was found to be readily
biodegradable in an OECD 301 F Manometric respiration test at an
application concentration of 100 mg/L. There was no evidence for
toxicity to bacteria. (Klimisch score : 2, for details of the study
please see chapter: 5.2.1, Evonik Industries 1999)
Furthermore the toxicity of
Ethyltriglycol methacrylate to microorganisms (Pseudomonas putida) was
evaluated in bacteria toxicity test according to Bringmann-Kühn
(modified DIN 38412, part 8) with limited documentation (Klimisch score:
4). The 16h-EC10 in this study was determined to be > 8000 mg/L for
Ethyltriglycol methacrylate (for details of the study please see
chapter: 6.1.7, Evonik Industries 1988).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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