Registration Dossier

Administrative data

Description of key information

The key study for acute oral toxicity reports an LD50 value of >5000mg/kg (Albert, 1981; rel 1). The rat 4 hour inhalational LC50 for alcohols C9-11-linear and branched  was found to be >0.237  mg/l (Blair 1981; rel 2). The acute dermal toxicity LD50 value is >1660 mg/kg (Albert 1981; rel 1).

Key value for chemical safety assessment

Additional information

The most reliable and recent studies were chosen as key information. High reliability supporting studies are in place for acute oral and dermal toxicity, further supporting the key findings. The LC50 value for acute inhalation represents a near saturated vapour concentration and is therefore deemed suitable for determining classification and labelling outcome. The dermal LD50 is >2 ml/kg which  is equivalent to 1660 mg/kg using a density of 0.83 for conversion. Other than irritation at the application site which was reversible within the 14 day observation period, there were no other signs of toxicity. Based on this and data on acute dermal toxicity across category on alcohols of this chain length, it is assumed here that no mortalities would have occurred at the application of 2000 mg/kg of the test substance.

In some cases the CAS and chemical identity stated refer to the SDA nomenclature for this substance. In REACH substance identification it is necessary to be more specific as to the chain lengths present. Full details may be found in the CSR.

Justification for classification or non-classification

Acute toxicity tests of the tested material (C9 -11 linear and branched) do not indicate any potential hazard for acute, dermal or inhalation toxicity. Tests on similar substances included in this category are also supportive of these results; which do not warrant classification for any acute toxicity endpoint under DSD or GHS criteria. The substance is therefore not classified for acute toxicity in accordance with EC regulation 1272/2008.