Registration Dossier
Registration Dossier
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EC number: 231-157-5 | CAS number: 7440-47-3
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Chromium is highly insoluble as demonstrate in the T/D test as a consequence: chromium (III) produces soluble (bio)available ionic and other chromium-bearing species in environmental media is limited. The insolubility of chromium (III) is expected to determine its behavior, its fate in the environment, and subsequently its ecotoxicity potency.
In accordance with ECHA’s Guidance on IR & CSA, Appendix R.7.13-2 (2008), the substance can be evaluated by comparing the dissolved chromium (III) ion level resulting from the T/D at a loading rate of 1 mg/L after 28-Days with the lowest chronic effect concentration as determined for the (soluble) chromium (III) ion. For comparison only, the lowest chronic toxicity data in the public domain, has been obtained on a soluble trivalent chromium and was reviewed in WHO CICAD (WHO 2009). They determined that 72-day NOEC in Oncorhynchus mykissis is ca. 0.005 mg/L (Stevens & Chapman, 1984). This data was obtained with the higher soluble form: chromium nitrate. The solubility of chromium (under different powder forms in 28-days T/D test) is ca. 0.005 µg/L. Dissolved chromium concentrations of <0.01 µg/L in the T/D after 28-Days at pH 6 (i.e. the pH that maximizes the dissolution) are significantly lower than the lowest chronic effect concentration derived for fish (i.e. NOEC of 30 µg Cr/L). Hence, chromium (III) is not sufficiently soluble in environmental media to cause chronic toxicity to fish at the level of the lowest chronic effect concentration (expressed as the NOEC).
According to this data, short-term toxicity on fish is not expected
Key value for chemical safety assessment
Additional information
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