Registration Dossier

Guidance on Safe Use

Guidance on Safe Use

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Administrative data

First-aid measures

Product-Specific hazards and other issues :
- This product is of low acute toxicity.
- High concentrations may cause anesthesia, asphyxia and possibly cardiac sensitization.
- Contains 1,3 butadiene.
- Product is genotoxic.
- May cause cancer by inhalation.
- Contact with liquid may cause frostbite.
- Remove contaminated clothes except in the case of frostbite.

General advice :
- Always observe self protection methods.
- Move out of dangerous area.
- Remove contaminated clothing and shoes.
- Get medical attention immediately.
- Show the material safety data sheet to the doctor in attendance.

Inhalation :
- Remove to fresh air and keep at rest in a position comfortable for breathing.
- Do not leave the victim unattended.
- Keep patient warm and at rest.
- Immediately seek medical attention.
- If breathing is difficult, give oxygen.
- If unconscious place in recovery position and seek medical advice.
- In the event of unconsciousness, apnea or cardiac arrest (no pulse) apply cardiopulmonary resuscitation.

Skin contact :
- Non-irritating to the skin.
- Dermal contact with rapidly evaporating liquid could result in freezing of the tissues or frostbite.
- If frostbite has occurred, seek medical attention immediately; do not rub the affected area or flush with water. To prevent further damage, do not attempt to remove frozen clothing from affected area.
- If frostbite has not occurred, immediately flush affected area with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
- Get medical attention immediately if irritation persists.

Eye contact :
- This gas is non-irritating; but direct contact with liquified/pressurized gas or frost particles may produce severe and possibly permanent eye damage from freeze burns.
- If eye tissue is frozen, seek medical attention immediately and provide for further treatment by an ophthalmologist due to possible burn of the eyes. Do not remove contact lenses.
- If tissue is not frozen, thoroughly flush the eyes with large amounts of clean low-pressure water for at least 15 minutes.
- Get medical attention immediately if irritation persists.

Ingestion :
- Not applicable (gas)

Advice to Physician :
- Treat symptomatically.
- Treatment of overexposure should be directed at the control of symptoms and the clinical condition of the patient.
- Inhalation of very high concentrations may cause asphyxia, anesthesia, CNS depression (primarily fatigue, dizziness and loss of concentration, with collapse, coma and death in cases of severe overexposure), and possible cardiac sensitization.
- Epinephrine and other sympathomimetic drugs may initiate cardiac arrhythmias (irregular beating) in persons exposed to this material.
- Skin or eye contact with rapidly evaporating liquid could result in freezing of the tissues or frostbite.
- Treat frost-bitten areas as needed.

Fire-fighting measures

Suitable extinguishing media:
Small fires :
- Use dry chemicals, CO2, water spray or alcohol-resistant foam
Large fires :
- Use dry chemicals, CO2, water spray or alcohol-resistant foam
- DO NOT extinguish a leaking gas flame unless the leak can be stopped. In many cases it will be preferable to allow continued burning.

Unsuitable extinguishing media :
- Do not use a solid water stream as it may scatter and spread fire.

Combustion products :
- Carbon dioxide, carbon monoxide, smoke, fumes and unburned hydrocarbons

Specific hazards during fire-fighting :
- May polymerize explosively when involved in a fire. Vapors may travel long distances along the ground before reaching a source of ignition and flashing back. Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. Do not direct water at source of leak or safety devices; icing may occur. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. Always stay away from tanks engulfed in fire. For massive fire, use unmanned hose holders or monitor nozzles; if this is impossible, withdraw from area and let fire burn.
- Move containers from fire area if you can do it without risk.
- Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations.


Further information :
- Use water spray to cool unopened containers.

Special protection equipment for fire-fighters :
- Wear an approved positive pressure self-contained breathing apparatus and firefighter turnout gear.

Accidental release measures

Personal precautions :
- Use personal protective equipment.
- Ensure adequate ventilation.
- Eliminate all sources of ignition.
- Evacuate personnel to safe areas.
- Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas.

Land spillage :
- Prevent product from entering drains.
- Prevent further leakage or spillage if safe to do so.

Spillages in water or at sea :
- If the product contaminates rivers and lakes or drains inform respective authorities.

Methods for cleaning up :
- Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations (see section 13).
- Eliminate all sources of ignition.
- Let evaporate.
- All equipment used when handling this product must be grounded.
- Stop leak if you can do it without risk.
- Isolate area until gas has dispersed.
- Water spray may reduce vapor; but may not prevent ignition in closed spaces.
- Prevent entry into waterways, sewers, basements or confined areas.
- Caution: When in contact with refrigerated/cryogenic liquids, many materials become brittle and are likely to break without warning.

Further accidental release measures :
- Spillages of liquid product will create a fire hazard and form an explosive atmosphere.
- Avoid direct contact with released material. Stay upwind.
- Keep non-involved personnel away from the area of spillage.
- Ensure adequate ventilation, especially in confined areas.

Handling and storage

Handling
Advice on safe handling :
- Do not handle near heat, sparks, or flame.
- Do not enter storage area unless adequately ventilated.
- Metal containers involved in the transfer of this material should be grounded and bonded.
- Bonding and grounding measures may not be enough if nonconductive flammables are involved.
- If exposure to liquid butadiene (unusual conditions, such as a leaking pressurized cylinder) were to occur, the rapid evaporation of this substance could cause severe cooling and damage to the skin in the form of frostbite.
- Check atmosphere for explosiveness and oxygen deficiencies.
- Wear recommended personal protective equipment.
- Handle empty containers with care; vapor residue may be flammable/explosive.
- Isolate, vent, drain, wash and purge systems or equipment before maintenance or repair.
- All equipment must conform to applicable electrical code.
- Use only non-sparking tools.
- Do not pressurize, cut, weld, braze solder, drill, or grind on containers.
- While moving cylinder, always keep in place removable valve cover.
- Securely chain cylinders when in use and protect against physical damage.

Advice on protection against fire and explosion :
- Take precautionary measures against static discharge.

Fire-fighting class :
- Extremely flammable gas.

Storage
- Keep storage containers clean, dry and free of oxygen.
- Monitor inhibitor (TBC) content to maintain appropriate concentration.
- Oxygen intrusion into the vessel headspace may support the formation of peroxides and promote popcorn polymer growth.
- Popcorn polymer may plug safety-venting devices, plug lines and foul equipment.
- Polymer formation may build sufficient mechanical force to rupture equipment.
- Store in tightly closed containers segregated from oxidizers and other combustible material.
- Store cylinders outdoors without direct sunlight or heat radiation and with adequate ventilation. - Provide electrical equipment with spark resistant construction.

Transport information

Land transport (ADR/RID)

UN number:
UN-Number : 1010
Shippingopen allclose all
Class:
Class : 2
Classification code:
Classification Code : 2F
Labels:
Labels : 2.1
SpecialProvisionsopen allclose all

Inland waterway transport (ADN(R))

UN number:
UN-Number : 1010
Shippingopen allclose all
Class:
Class : 2
Classification code:
Classification Code : 2F
Labels:
Labels : 2.1
Remarksopen allclose all

Marine transport (IMDG)

UN number:
UN-Number : 1010
Proper shipping name and description:
Description of the goods : BUTADIENES AND HYDROCARBON MIXTURE, STABILIZED
Chemical name:
Hydrocarbons, C4, ethylene-manuf.-by-product
Class:
Class : 2
Labels:
Labels : 2.1
Remarksopen allclose all
Remarksopen allclose all
SpecialProvisionsopen allclose all

Exposure controls / personal protection

Engineering measures :
- Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits.

Personal protective equipment:
Respiratory protection :
- When workers are facing concentrations above the exposure limit they must use appropriate certified respirators.
- The type of respiratory protection will depend upon whether the maximum exposure concentration is known.
- If needed, wear a supplied air respirator conforming to a European norm standard such as EN 139 or equivalent.
- Wear a respirator conforming to EN 371 with Type AX filter designed for low boiling compounds.

Hand protection :
- Wear insulated gloves if contact with liquid is possible.
- The selected gloves must satisfy the European norm standard EN 511 for protection against the cold.

Eye protection :
- Wear safety glasses as minimum protection.
- Use chemical type goggles and face shield when handling liquefied gases.
- The selected goggles or glasses must satisfy the European norm standard EN 166.

Skin and body protection :
-Clothing such as insulated impervious gloves to protect against exposure to cold liquid or gas should be worn.
- Choose body protection according to the amount and concentration of the dangerous substance at the work place.
- Use PPE that is chemical resistant to the product and prevents skin contact.


Hygiene measures :
- Selection of appropriate personal protective equipment should be based on an evaluation of the performance characteristics of the protective equipment relative to the task(s) to be performed, conditions present, duration of use, and the hazards and/or potential hazards that may be encountered during use.
- Consult the appropriate European norm (EN) standard before deciding on the type of personal protective equipment that is appropriate for a particular set of circumstances.
- Emergency eye wash fountains and safety showers should be available in the immediate vicinity of any potential exposure.
- Use good personal hygiene practices.
- Wash hands before eating, drinking, smoking, or using toilet facilities.
- Take off contaminated clothing and wash before reuse.

Environmental exposure controls
-An authoritative evaluation of environmental exposure and risk indicates that no special risk management practices are needed to control environmental release.

Stability and reactivity

Chemical stability :
- Unstable.
- May be able to form unstable peroxides.
- The product is normally supplied in a stabilized form. If the permissible storage period and/or storage temperature is noticeably exceeded, the product may polymerize with heat evolution.

Conditions to avoid :
- All sources of ignition, high temperature and oxygen intrusion into storage and transportation vessels. Elevated temperature or catalysis can cause violent rupture of containers.

Materials to avoid :
- Reacts vigorously with oxidizing materials
- Phenol, ethanol, chlorine dioxide, crotonaldehyde, nitric acid, oxygen and other strong oxidizers, and acetylide forming materials such as copper, magnesium, mercury, silver and monel. Contact may form violently explosive peroxides.

Hazardous decomposition products :
- Incomplete combustion can result in the production of carbon monoxide, carbon dioxide and other toxic gases.

Thermal decomposition :
- Thermal decomposition may produce oxides of carbon and other toxic gases and liberate heat and pressure.

Hazardous polymerization :
- Polymerization may take place at elevated temperatures or in the presence of oxidizers. The formation of popcorn polymer can build sufficient mechanical force to rupture process equipment. - Polymer may also plug safety venting devices.

Reactions with Air and Water :
- May be able to form unstable peroxides.

Disposal considerations

- Contaminated product, soil, water, container residues and spill cleanup materials may be hazardous wastes.
- The product should not be allowed to enter drains, water courses or the soil.
- Comply with applicable local, state or international regulations concerning solid or hazardous waste disposal and/or container disposal.
- Contaminated product, soil or water should be considered dangerous due to potential evolution of flammable vapor.
- Proper grounding procedures to avoid static electricity should be followed.