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Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1982
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed
Year:
1982

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
not specified
Test type:
other: LC50

Test material

Constituent 1
Chemical structure
Reference substance name:
Trichlorosilane
EC Number:
233-042-5
EC Name:
Trichlorosilane
Cas Number:
10025-78-2
Molecular formula:
Cl3HSi
IUPAC Name:
trichlorosilane

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
other: no data
Type of inhalation exposure:
not specified
Vehicle:
other: no data
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
2 h
Concentrations:
No data
No. of animals per sex per dose:
No data
Control animals:
not specified

Results and discussion

Effect levels
Dose descriptor:
LC50
Effect level:
1.5 mg/L air
Based on:
test mat.
Exp. duration:
2 h

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
In an acute inhalation toxicity study, not conducted according to OECD Test Guideline and not specified if in compliance with GLP, a 2-hour LC50 value of 1.5 mg/l in the mouse was reported in IUCLID 2000. No further details are available.

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