Registration Dossier

Administrative data

Endpoint:
dermal absorption
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Accepted calculation method
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other: QSAR Database
Title:
Unnamed
Year:
2012
Report Date:
2012

Materials and methods

Test guideline
Guideline:
other: REACH guidance on QSARs R.6, May/July 2008
Principles of method if other than guideline:
Dermwin v2.01 (Q)SAR database report

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Absorption in different matrices:
Dermal absorption of the test substance was predicted to be very low with an estimated dermal permeability coefficient (Kp) of 0.00222 cm/h and a dermal absorption rate of 0.00076 mg/cm²/h (=0.000189 mg/cm²/event).

Applicant's summary and conclusion