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Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

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Description of key information

LC50 (14d) > 1000 mg/kg dw for Eisenia fetida (OECD 207)

Key value for chemical safety assessment

Additional information

There are no studies available on the toxicity of Reaction products resulting from the esterification of Sorbitol with C8-18 (even) and C18unsaturated fatty acids in the ratio 1:1 (EC 931-434-7) on terrestrial macroorganisms. In accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5, the assessment was therefore based on studies conducted with the structurally related category members Sorbitan, octanoate (2:3) (CAS No. 91844-53-0) and Anhydro-D-glucitol trioleate (CAS No. 26266-58-0). These read across are justified in detail in the overall summary (IUCLID chapter 6.3) and within the category justification in IUCLID Section 13.

The key study conducted with Sorbitan, octanoate (2:3) (CAS No. 91844-53-0), was performed as a limit test according to OECD guideline 207 and GLP, in a static system (Simon, 2013). The test organism Eisenia fetida was exposed to a test concentration of 1000 mg/kg dry soil. No mortality occurred, and the EC50 was determined to be > 1000 mg/kg.

The key study conducted with Anhydro-D-glucitol trioleate (CAS No. 26266-58-0) was performed as a limit test according to OECD guideline 207 and GLP (Harris, 2012). The test organism Eisenia fetida was exposed to the test substance in artificial soil for 14 days, at the nominal test concentration 1000 mg/kg. No mortality occurred during the test period.